The Economist Magazine Cover from 1992 is about Gene Modification

The Economist Magazine Cover from 1992 is about Gene Modification

Gene Therapy is Genetic Modification

Gene therapy and gene modification are related concepts but have distinct purposes. Gene therapy aims to alter genes to correct genetic defects and prevent or cure genetic diseases. It involves modifying the genome of specific cells to treat or prevent a genetic condition, often using a viral delivery system to introduce a functional gene into the patient’s genome.

The potential risks of gene therapy include:

  1. Unwanted immune system reaction: The body’s immune system may see the introduced viruses as intruders and attack them, leading to inflammation and, in severe cases, organ failure[1].
  2. Targeting the wrong cells: Viruses used as vectors in gene therapy can affect more than one type of cells, potentially leading to unintended consequences[1].
  3. Toxicity, inflammation, and cancer: Early studies showed that gene therapy could have serious health risks such as toxicity, inflammation, and cancer. However, improved techniques have been developed to mitigate these risks[2].
  4. Unpredictable risks: Due to the relative novelty of gene therapy techniques, some risks may be unpredictable. However, rigorous research, regulations, and clinical trials are in place to ensure safety[2].

It’s important to note that gene therapy is a rapidly evolving field, and ongoing research is focused on addressing these risks to ensure the safety and effectiveness of the treatment[3].

Citations:
[1] https://www.mayoclinic.org/tests-procedures/gene-therapy/about/pac-20384619
[2] https://medlineplus.gov/genetics/understanding/therapy/safety/
[3] https://www.verywellhealth.com/gene-therapy-5214362
[4] https://code-medical-ethics.ama-assn.org/ethics-opinions/research-gene-therapy-genetic-engineering
[5] https://medicine.missouri.edu/centers-institutes-labs/health-ethics/faq/gene-therapy